Sterol 14α-Demethylase from Trypanosomatidae Parasites as a Promising Target for Designing New Antiparasitic Agents

Strategies for the Synthesis of Mono- and Bis-Thionaphthoquinones

Trypanosomatidae household belongs to the Kinetoplastida order, which consists of compulsory parasites that have an effect on crops and all courses of vertebrates, particularly people and bugs. Among the heteroxenic parasites, Leishmania spp., Trypanosoma cruzi, and T. brucei are protozoa of most important curiosity for medicinal chemistry, being etiological brokers of Leishmaniasis, Chagas, and Sleep … Read more

Ohmic heating increases inactivation and morphological changes of Salmonella sp. and the formation of bioactive compounds in infant formula

Ohmic heating increases inactivation and morphological changes of Salmonella sp. and the formation of bioactive compounds in infant formula

The impact of ohmic heating (OH) (50, 55, and 60 °C, 6 V/cm) on the inactivation kinetics (Weibull mannequin) and morphological changes (scanning electron microscopy and stream cytometry) of Salmonella spp. in infant formula (IF) was evaluated. In addition, thermal load indicators (hydroxymethylfurfural and whey protein nitrogen index, HMF, and WPNI) and bioactive compounds (DPPH, complete phenolics, ACE, … Read more